A £480,000 project to improve Langwathby Bridge and the road through the village is set to start on Monday.
The road closed at Langwathby Bridge to the Shepherds Inn will close until September 23.
During this time, from the Shepherds Inn to the junction of the B6412 Culgaith the road will also be closed for up to two weeks to facilitate a further phase of resurfacing work, although the exact dates are yet to be confirmed.
Access for local businesses and affected residents will be arranged with the contractor.
The work includes a full depth reconstruction of the road foundations from the bridge for about 100 metres towards the village, resurfacing from the bridge to the junction of the B6412 Culgaith and work to resolve a long-standing issues with the bridge deck on structure.
The Coast to Coast route will be unaffected and a safe way through the works for pedestrians and dismounted cyclists will be maintained.
A fully signed diversion will also be in place throughout along with ‘open for business’ signs.
Claire Driver, Cumbria County Councillor for Alston and East Fellside said: “The essential work on the bridge which will last around eight weeks has been programmed to run in parallel with the road works through the village to avoid separate closures of eight and four-week periods at a later date.
“Whilst there is never a good time to close a road, our contractors have to work around the environmental window for river works and also when the weather is better to help the material to cure.
“I would like to thank residents, businesses and visitors in advance for their patience and co-operation whilst this work is carried out which will greatly improve the road surface condition for many years to come.”